Pre-Clinical Studies

Preclinical studies are required for evaluating the candidate drug molecules safety and efficacy during the animal testing mandated by the FDA. Pre-clinical studies deal with wide array of toxicological and preclinical protocols at biochemical, cellular, and molecular levels for the screening of drugs, pharmaceuticals & nutraceuticals, novel therapeutic agents and other materials. We, as a CRO, provide services for the arrangement of pre-clinical studies and toxicological testing services with robust scientific expertise, numerous in life and end point measurements and customizable study design for evaluation of drugs & novel agents. We have also recently expanded our services to facilitating experimental diseased models using wild type and genetically modified rodents to explore new biomarkers, therapeutic agents, and mechanism of action at cellular and molecular levels followed by preclinical and toxicological studies. We also arrange pre-clinical studies for testing of safety and efficacy of biomedical and biotechnological devices. 

Some of the services we provide are listed below: 
  • Hepatocellular carcinoma (HCC) model in rats to chronologically analyze steps of hepatocarcinogenesis for investigating the effects of novel anti-cancer agents.
  • Hyperlipidaemia, atherosclerosis, and inflammatory models to develop novel anti-inflammatory agents using nanoparticle-based formulation from natural products.
  • Deep Wound and Topical Skin Infection Models.
  • Murine Model of Neutropenic Thigh Infection
  • Pulmonary sepsis model
  • Cecal ligation and puncture
  • LPS-induced peritonitis model
  • Murine Urinary Tract Infection (UTI) Models
  • Acute and Chronic Models of Lung Infection
  • Various inflammatory and Immune based models
  • Safety and efficacy testing of medicated ointments, cosmeceutical products
  • Wound healing
  • Safety and efficacy testing for biomedical and biotechnological devices